Society of Women Engineers, Boston Section - September Meeting
Engineering the Future – Using Nanosensors to Monitor Glucose and Cardiac Function
Sponsored by The Charles Stark Draper Laboratory
Join fellow SWE members and guests for an overview of how researchers at The Charles Stark Draper Laboratory are working to improve the lives of diabetics and cardiac patients. Draper has developed several types of nanosensors aimed at measuring ion and small molecule concentrations in the intracellular and extracellular environment. These nanosensors are composed of a variety of chemistries contained in a fluorescent, plasticized-polymer bead. The beads are produced in house in minutes, and can easily be modified to change the concentration range and detectable analytes. Currently, Heather’s group focuses on two applications: intracellular sodium dynamics in cardiac cells and a nanosensor “tattoo” for monitoring glucose levels in diabetics.
Diabetes mellitus refers to the group of diseases in which the body suffers from a diminished production of or resistance to insulin, which regulates the storage of glucose as glycogen in the liver and muscles. In order to avoid elevated blood sugar levels and serious health complications, diabetic patients must periodically monitor their glycemic levels throughout each day via a technique that is unfortunately both painful and inconvenient. In an attempt to address these issues, Draper has designed fluorescence-based nanosensors that successfully monitor glucose in vitro as well as in vivo. Glucose levels are efficiently detected in the hypo- and hyperglycemic range, and chemical interferents, which are problematic for commercially available enzyme-based systems, do not affect the response. The optical nanosensors offer continuous analysis of glycemic levels in vivo through a minimally invasive process and provide a beneficial alternative to traditional methods for diabetics to measure blood sugar concentration.
RSVP by September 15, 2009 via Acteva
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Date:Tuesday, September 22, 2009
The Charles Stark Draper Laboratory
$10 Non-working members
$15 SWE members
Free for Charles Stark Draper Laboratory employees
About our Speaker:
Heather Clark is a Principal Member of the Technical Staff in the Biomedical Engineering Group at the Charles Stark Draper Laboratory. Her work focuses on the application of optical techniques to biological systems, specifically the development of a novel nano-scale biosensor array to measure cellular ion flux in response to external stimuli. Previous research includes the development of an optical nanosphere sensor for use in intracellular analyses and an NIH-sponsored Postdoctoral Fellowship centered on combining optical imaging technologies with electrophysiology. Dr. Clark earned a BS in Chemistry and a PhD in Analytical Chemistry from the University of Michigan.
About our Sponsor - The Charles Stark Draper Laboratory
Headquartered in Cambridge, Massachusetts, The Charles Stark Draper Laboratory is a research and development laboratory, employing more than 850 engineers, scientists, and technicians on a broad array of programs for government and commercial sponsors among its 1,384 employees.
Its sponsored work encompasses capabilities in the following business areas:
• Strategic Systems
• Space Systems
• Tactical Systems
• Special Operations
• Biomedical Engineering
• Geospatial Solutions
• Energy Solutions
Additional information can be found on their website, http://www.draper.com
Location: The Charles Stark Draper Laboratory
Validated parking is available in the Technology Square garage across from the Draper visitor entrance. It is the second garage entrance on the right from the Broadway entrance to Tech Square. Please make sure you bring your parking ticket with you to the meeting.